Saturday, 19 December 2020

Experts give a chance to amantadine

A doctor from przemysl says that amantandin helps patients with covid-19. Experts say in the media that only so it seems to him. meanwhile, professor caesar pakulsky, who treats other diseases with amantadine in the intensive care unit, urges not to apply double standards in her case
Tens of thousands of Polish women and Poles are infected with the SARS-CoV-2 virus every day. In a significant part of them, the disease passes slightly, sometimes even asymptomatically. someone is seriously ill, someone is dying. Of those who were seriously ill, but they managed to survive, most of the quality of life will not return to what it was before the disease. extensive and irreversible non-inflammatory changes in the lungs that occur during the course of the disease do not go away.



Covid-19 caught everyone by surprise. There was no time to look for new drugs and treatments for SARS-CoV-2 infection. All attention was turned to the search for indications for the treatment of COVID-19 with previously known drugs. Chloroquine, hydrochloroquine, Azithromycin, favipiravir, Famotidine, interferon, Kaletra-their therapeutic effectiveness was believed. Their widespread use in the treatment of covid-19 has been made possible by the recognition of these treatments as a permitted medical experiment.All this is due to the deterioration of the economy, among other things. In connection with the quarantine, the question of work is acute,and many move to the online sphere, knowing that you can earn additional income, as
deltamarket reviews does . Many professions in connection with the pandemic were called into question.

After a shorter or longer period of infatuation, the following drugs were found to have no positive therapeutic effect, while causing adverse reactions related to their pharmacological profile. One by one, it was removed from the list of experimental drugs.


At first we were helpless.


The choice of drugs used was not and is not any idea of doctors. In April 2020, the Agency for the Assessment and Pricing of Medical Technologies (aotmit) published the document"Polish diagnostic, therapeutic and organizational recommendations for the care of persons infected or at risk of SARS-CoV-2 infection". It is constantly updated and has been prepared by Polish specialists in many fields of medicine on the basis of available research results.

At the very beginning, its authors therapeutically made key decisions based on the results of poorly designed, mutually exclusive and performed on small groups of patients comparative studies or non-randomized observational work. These were the only possibilities.

The document is striking in its apparent helplessness against the virus. This shows that in the fight against covid-19, we can only rely on oxygen, respirators and treatment by changing the position of the body (alternating the position of the body on the back and on the stomach). Also advancing to the technique of extracorporeal blood oxygenation (WAKO). for those who believe, there is still prayer.


The next weeks and months will bring new disappointments.

Today, we do not have a single drug that can be called effective in the treatment of sars-cov-2 infection.

Ramdevpir also not working


Even remdesivir, a drug that until a few weeks ago was the only effective treatment for covid-19, according to the World Health Organization (WHO), does not prevent death from covid-19. This also does not prevent the transition of the disease to a severe phase and the need to start respiratory therapy with a respirator, therefore ... it doesn't work. We are still waiting for the publication of the results of studies conducted in Polish infectious diseases departments. As previously reported, the results of ongoing studies are designed to confirm the effectiveness of remdesivir therapy, but only if it is used at a very early stage of the disease. at this early stage of treatment, oxygen therapy should be included in the course of treatment.

This is bad news because it means that the treatment Redecision should be initiated in all patients admitted for inpatient treatment. We never know how aggressive the disease will be. The cost of treatment of one patient is almost 10 thousand zlotys, but even if we as a country had sufficient financial resources, by the end of the year Polish hospitals will receive 96 thousand packages of the drug, which means the possibility of treating up to 16 thousand patients.

Several well-developed multicenter studies are currently underway that will ultimately decide whether treatment with azithromycin, curative plasma, tocilizumab, or monoclonal antibodies is effective. it should be expected that all of them will be considered ineffective in the treatment of sars-cov-2 infection.

In conclusion, this entire section on the pharmacotherapy of patients with COVID-19 should end with the ominous conclusion that SARS-CoV-2 infections have nothing to treat. we don't have a cure for this infection, we still don't have access to a vaccine. we only treat the symptoms.

Exceptions that reduce the risk of complications in severe covid-19 are anticoagulant heparin drugs, and in patients who already need treatment in the intensive care unit, in addition, a steroid drug (dexamethasone).

The health care system is in decline


At the same time, the pandemic is gaining momentum. The number of infected people, patients receiving treatment at home, in hospitals, patients who need respiratory support with a respirator, and finally those who die in hospitals is growing. Due to the depletion of local and state capacity of the system, patients also die at home and on the way to the hospital. Hospitals are queuing up patients waiting to be connected to a free respirator, and at the same time, a temporary hospital in Warsaw is proving to be the most expensive national isolation facility in Poland.

The health care system in many places simply doesn't exist anymore. In this reality, sick people and their families begin to function. With overcrowded hospitals, hard-to-reach surgery rooms, and a growing number of doctors in isolation due to SARS-CoV-2 infection, healthy people are finding it increasingly difficult to live and patients are losing their ability to cope.


There are more and more descriptions in the press of situations in which covid-19 patients or patient families complain that the state and the health care system have abandoned them. For example, a doctor, explaining himself with meaningless procedures, refuses to come to visit a patient in poor condition with a potential covid-19. He says that it is not possible to organize the collection of smears at the place of stay of the patient and suggests calling an ambulance instead. If you have already managed to call 112, the dispatcher says that the ambulance does not conduct such visits, and a visit to a seriously ill person is the duty of the doctor pos.a repeated call to the pos polyclinic at best ends with an order for telephone antibacterial therapy "just in case". Then it turns out that there is no one to buy this antibiotic.